More than eight months after Nancy Guthrie disappeared from her Arizona home, investigators are continuing to examine forensic evidence and pursue leads in a case that has yet to produce a publicly identified suspect.

A new report published on October 28, 2026, says members of the task force traveled to a forensic laboratory in Florida as investigative work continues. The visit highlights the continuing role of DNA analysis in the effort to establish what happened to Guthrie, the 84-year-old mother of Today co-anchor Savannah Guthrie.

DNA EVIDENCE REMAINS A KEY FOCUS
Guthrie was last seen at her home in the Catalina Foothills area near Tucson on the night of January 31, 2026. She was reported missing the following day, prompting a major investigation involving the Pima County Sheriff’s Department and the FBI.

Authorities have previously confirmed that blood found outside her home belonged to Guthrie. Investigators also collected other evidence for forensic testing, including DNA material that did not match her or some people known to have been in close contact with her.

The decision to process evidence at a Florida laboratory drew public attention earlier in the investigation. Sheriff Chris Nanos defended the choice, explaining that his department had worked with the lab for years and that using one facility allowed investigators to compare samples and coordinate reports. He said at the time that some DNA results had been returned, but they had not led to a suspect.

The FBI and local authorities have also faced public questions about how evidence was handled during the early days of the case. Both agencies have continued to be involved, while the sheriff’s department has maintained that the investigation remains active.

SURVEILLANCE FOOTAGE AND PUBLIC TIPS
The FBI previously released surveillance images showing a masked individual near Guthrie’s front door around the time she disappeared. Investigators have also reviewed a substantial volume of video, photographs and tips from the public.

In August, the sheriff’s department said the case remained active and that forensic laboratories across the country were working together on DNA evidence. Officials also described the continuing review of digital material as an important part of the investigation.

Authorities have not publicly announced an arrest or identified a suspect in connection with Guthrie’s disappearance.

QUESTIONS REMAIN ABOUT THE 911 CALL
The original 911 call made when Guthrie was discovered missing has not been publicly released. A report published on October 28 says the recording remains private, but the available information does not establish a new official decision about its release or confirm what the recording contains.

The lack of publicly available details means it would be premature to draw conclusions about what the call might reveal. Investigators have not publicly disclosed every piece of evidence gathered in the case.

THE INVESTIGATION REMAINS OPEN
In late September, the Pima County Sheriff’s Department said investigators had reviewed a new possible ransom-related text message with the FBI and determined it was not credible. Officials urged anyone receiving communications related to Guthrie’s disappearance to report them to law enforcement.

The latest reported visit to the Florida laboratory suggests that forensic work remains part of the ongoing effort to find answers. However, no public confirmation has established that the visit produced a breakthrough, identified a suspect or resulted in a new conclusion about Guthrie’s whereabouts.

For now, investigators continue to seek information that could clarify what happened after Guthrie was last seen at home. The case remains unresolved, and authorities have not publicly announced a major breakthrough.

SOURCES

KVOA — Day 265 of Nancy Guthrie case: Task force visits Florida lab (provided article link; access was restricted).